RAYNAUD'S DISEASE ASSOCIATED WITH CHRONIC ARSENICAL RETENTION
- 5 April 1930
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 94 (14) , 1035-1037
- https://doi.org/10.1001/jama.1930.02710400007002
Abstract
One of the most interesting and significant of recent developments in medicine has been the work of Throne and Myers1on the relation of arsenical retention to the genesis of eczema. At the New York Skin and Cancer Hospital they have demonstrated the presence of arsenic in 30 per cent of the cases of this disease. That arsenic is the main pathogenic factor in these cases is shown by the high percentage of cures obtained with sodium thiosulphate. The work of these investigators, however, has gone a great deal further than the successful treatment of a number of hitherto refractory cases. Many highly suggestive facts have been brought out. In the first place it is quite characteristic for a case of arsenical eczema, when first seen, not to show arsenic in the urine. A twenty-four hour specimen of urine collected after the intravenous injection of 0.5 Gm. of sodiumKeywords
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