Molecularly assessed shifts ofBifidobacteriumssp. and less diverse microbial communities are characteristic of 5-year-old allergic children
Open Access
- 1 November 2007
- journal article
- Published by Oxford University Press (OUP) in FEMS Immunology & Medical Microbiology
- Vol. 51 (2) , 260-269
- https://doi.org/10.1111/j.1574-695x.2007.00306.x
Abstract
The composition of intestinal microbiota and the Bifidobacterium group community in 20 allergic and 20 nonallergic 5-year-old children was visualized by PCR-denaturing gradient gel electrophoresis (DGGE). The number of dominant bands in the DGGE profiles was smaller in allergic children than in nonallergic children (PBifidobacterium adolescentis species prevailed, and in nonallergic children the Bifidobacterium catenulatum/pseudocatenulatum prevailed (P=0.01 and P=0.01, respectively). The less diverse composition of intestinal microbiota and prevalence of particular species of Bifidobacterium were characteristic of allergic children even at the age of 5 years.Keywords
This publication has 29 references indexed in Scilit:
- Meat as a First Complementary Food for Breastfed Infants: Feasibility and Impact on Zinc Intake and StatusJournal of Pediatric Gastroenterology and Nutrition, 2006
- Genetic Diversity of Viable, Injured, and Dead Fecal Bacteria Assessed by Fluorescence-Activated Cell Sorting and 16S rRNA Gene AnalysisApplied and Environmental Microbiology, 2005
- Innate Immune Responses of Human Neonatal Cells to Bacteria from the Normal Gastrointestinal FloraInfection and Immunity, 2002
- Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?Gut, 2002
- Current Understanding of Gastrointestinal Immunoregulation and Its Relation to Food AllergyAnnals of the New York Academy of Sciences, 2002
- Probiotics in the management of atopic eczemaClinical and Experimental Allergy, 2000
- Analysis of Intestinal Flora Development in Breast-Fed and Formula-Fed Infants by Using Molecular Identification and Detection MethodsJournal of Pediatric Gastroenterology and Nutrition, 2000
- Atopic versus infectious diseases in childhood: a question of balance?Pediatric Allergy and Immunology, 1997
- Identification and quantification of Bifidobacterium species isolated from food with genus-specific 16S rRNA-targeted probes by colony hybridization and PCRApplied and Environmental Microbiology, 1997
- Healthy individuals possess circulating antibodies against their indigenous faecal microflora as well as against allogenous faecal microflora: an immunomorphometrical studyEpidemiology and Infection, 1993