Measurement of lactate accumulation by in Vivo proton NMR spectroscopy during global cerebral ischemia in rats
- 1 October 1987
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 5 (4) , 353-357
- https://doi.org/10.1002/mrm.1910050406
Abstract
In vivo 1H NMR spectral editing techniques were used to monitor cerebral lactate production during remotely controlled temporary forebrain ischemia in rats. The lactate/N‐acetylaspartate (NAA) ratio correlated with survival after ischemia and subsequent reperfusion. The lactate/NAA ratio that predicted death after ischemia in rats was estimated to be approximately 1.3. © 1987 Academic Press, Inc.This publication has 10 references indexed in Scilit:
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