High Pressure, Diazepam and pH Influences on Ketamine Anaesthesia in the Rat
- 1 August 1980
- journal article
- research article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 24 (4) , 310-313
- https://doi.org/10.1111/j.1399-6576.1980.tb01554.x
Abstract
Ketamine infusion anaesthesia was studied in rats breathing oxygen/helium under hyperbaric conditions from 1 to 90 ATA. No pressure reversal of the analgesic effect was found. Premedication with diazepam failed to improve the analgesic action of ketamine, but influenced the respiratory pattern. Blood‐gas analyses showed a marked relationship between arterial pH and the ketamine dose requirement for stable anaesthesia.This publication has 13 references indexed in Scilit:
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