Clinical value of early cleavage embryo
- 4 January 2002
- journal article
- research article
- Published by Wiley in International Journal of Gynecology & Obstetrics
- Vol. 76 (3) , 293-297
- https://doi.org/10.1016/s0020-7292(01)00591-4
Abstract
Objective: This study was undertaken to see if embryo transfer containing early cleavage embryos resulted in better clinical pregnancy rate. Method: The treatment outcomes of IVF‐ET were retrospectively reviewed. Out of 258 transfer cycles, 160 cycles contained no early cleavage embryos (Group I) and 98 cycles contained at least one early cleavage embryo (Group II). The definition of early cleavage embryo is the presence of two blastomeres 24–26 h after insemination. The implantation rate, clinical pregnancy rate were compared between two groups. Student's t‐test and the Mann–Whitney U‐test were used for continuous variables, and the Chi‐squared (χ2) test was used for binary variables. Differences were considered statistically significant at PResult: The implantation rate and clinical pregnancy rate were 11.6% and 25.6% in Group I, 18.6% and 38.8% in Group II (PConclusion: Early cleavage embryos possess greater implantation potential. Embryo transfer containing early cleavage embryos had a better clinical pregnancy rate.Keywords
This publication has 22 references indexed in Scilit:
- Less is more: the risks of multiple birthsFertility and Sterility, 2000
- Reducing the Risk of Multiple Births by Transfer of Two Embryos after in Vitro FertilizationNew England Journal of Medicine, 1998
- Maximizing Pregnancy Rates and Limiting Higher-Order Multiple Conceptions by Determining the Optimal Number of Embryos to Transfer Based on QualityFertility and Sterility, 1998
- How Does Multiple Pregnancy Affect Maternal Mortality and Morbidity?Clinical Obstetrics and Gynecology, 1998
- Embryo developmental stage at transfer influences outcome of treatment with intracytoplasmic sperm injectionJournal of Assisted Reproduction and Genetics, 1997
- Implantation: Embryo score to predict implantation after in-vitro fertilization: based on 957 single embryo transfersHuman Reproduction, 1995
- Costs of triplet pregnancyAmerican Journal of Obstetrics and Gynecology, 1995
- Embryo growth ratein vitro as an indicator of embryo quality in IVF cyclesJournal of Assisted Reproduction and Genetics, 1994
- The Economic Impact of Multiple-Gestation Pregnancies and the Contribution of Assisted-Reproduction Techniques to Their IncidenceNew England Journal of Medicine, 1994
- Elective transfer of two embryosThe Lancet, 1991