(2S,4S)-2-Amino-4-(4,4-diphenylbut-1-yl)- pentane-1,5-dioic Acid: A Potent and Selective Antagonist for Metabotropic Glutamate Receptors Negatively Linked to Adenylate Cyclase
- 1 January 1996
- journal article
- letter
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 39 (4) , 814-816
- https://doi.org/10.1021/jm9508144
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Synthesis of Enantiomerically Pure 4-Substituted Glutamic Acids and Prolines: General Aldol Reaction of Pyroglutamate Lactam Lithium Enolate Mediated by Et2O.cntdot.BF3The Journal of Organic Chemistry, 1995
- L-2-amino-3-phosphonopropionic acid competitively antagonizes metabotropic glutamate receptors 1α and 5 in Xenopus oocytesEuropean Journal of Pharmacology: Molecular Pharmacology, 1995
- Distribution and Ontogeny of 1S,3R‐1‐Aminocyclopentane‐1,3‐Dicarboxylic Acid‐Sensitive and Quisqualate‐Insensitive [3H]Glutamate Binding Sites in the Rat BrainJournal of Neurochemistry, 1994
- Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor familyEuropean Journal of Pharmacology: Molecular Pharmacology, 1994
- Metabotropic glutamate receptors in brain function and pathologyTrends in Pharmacological Sciences, 1993
- Molecular Diversity of Glutamate Receptors and Implications for Brain FunctionScience, 1992
- Aldol reactions of pyroglutamates: chiral synthesis of 4.alpha.(S)- and 4.beta.(R)-(arylmethyl)pyroglutamatesThe Journal of Organic Chemistry, 1992
- Stereoselective synthesis of 3-alkylated glutamic acids: application to the synthesis of secokainic acidThe Journal of Organic Chemistry, 1991
- GABA-uptake inhibitors: construction of a general pharmacophore model and successful prediction of a new representativeJournal of Medicinal Chemistry, 1991
- An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusatesLife Sciences, 1988