INFLUENCE OF PERFUSION AND MECHANICAL-ACTIVITY ON ORNITHINE DECARBOXYLASE ACTIVITY IN THE ISOLATED RAT-HEART

  • 1 January 1979
    • journal article
    • research article
    • Vol. 23  (1) , 195-198
Abstract
An insignificantly small decrease in ornithine decarboxylase activity occurred in isolated rat hearts during 1 h of recirculating perfusion with Krebs-Henseleit solution. A significantly greater decrease occurred with a non-recirculating system. Ornithine decarboxylase activity was the same in the working heart preparation as in the non-working preparation. A substance, necessary for the maintenance of ornithine decarboxylase, was removed during perfusion. The nature of the mechanical activity of the heart apparently was not a determining factor.

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