Fibroblast Growth Factors and Their Receptors in Oligodendrocyte Development: Implications for Demyelination and Remyelination
- 1 July 2002
- journal article
- review article
- Published by S. Karger AG in Developmental Neuroscience
- Vol. 24 (1) , 35-46
- https://doi.org/10.1159/000064944
Abstract
Fibroblast growth factors are a family of broad-spectrum growth factors influencing a plethora of cellular activities. The interaction of at least 23 ligands, 4 receptors and multiple coreceptors provides a dramatic complexity to a signaling system capable of effecting a multitude of responses. This review focuses on the fibroblast growth factors signaling in oligodendrocyte development, function and discusses implications for demyelination/remyelination.Keywords
This publication has 30 references indexed in Scilit:
- Distinct roles for PI3K in proliferation and survival of oligodendrocyte progenitor cellsJournal of Neuroscience Research, 2000
- Fibroblast growth factors-5 and -9 distinctly regulate expression and function of the gap junction protein connexin43 in cultured astroglial cells from different brain regionsGlia, 2000
- From Neural Stem Cells to Myelinating OligodendrocytesMolecular and Cellular Neuroscience, 1999
- Heparin Is a Unique Marker of Progenitors in the Glial Cell LineageJournal of Biological Chemistry, 1999
- Functions of Cell Surface Heparan Sulfate ProteoglycansAnnual Review of Biochemistry, 1999
- Contrasting effects of mitogenic growth factors on oligodendrocyte precursor cell migrationGlia, 1997
- Receptor Specificity of the Fibroblast Growth Factor FamilyJournal of Biological Chemistry, 1996
- Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells derived from adult rat spinal cord: In vitro characteristics and response to PDGF, bFGF and NT-3Glia, 1996
- The oligodendrocyte and its many cellular processesTrends in Cell Biology, 1993
- FGF modulates the PDGF-driven pathway of oligodendrocyte developmentNeuron, 1990