Meningo-Encephalitis in Young Chickens Resulting from Infection with an Ornithosis Agent

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Abstract
An ornithosis agent of relatively low virulence was isolated from the brains of 2-day-old chickens having nervous symptoms similar to those associated with avian encephalomyelitis. Histopathologic changes in the brains consisted of meningitis, vasculitis, neuronal degeneration, and gliosis. A disease with brain lesions similar to the ones observed under field conditions was produced in young chickens by inoculation with the isolated ornithosis agent.