Simulation of Primary Haemostasis in vitro
- 1 January 1985
- journal article
- research article
- Published by S. Karger AG in Pathophysiology of Haemostasis and Thrombosis
- Vol. 15 (6) , 357-362
- https://doi.org/10.1159/000215173
Abstract
Primary haemostasis was simulated in vitro under standardized geometrical, rheological and biochemical conditions. The system was based on the hypothesis that adenine nucleotides, especially adenosine 5′-diphosphate, released from injured vessel wall cells play an important role for the initial platelet aggregation following lesion of small vessels. The device allows the reproducible measurement of in vitro bleeding time and volume in small samples of whole blood.Keywords
This publication has 2 references indexed in Scilit:
- Source and concentration of extracellular adenosine triphosphate during haemostasis in rats, rabbits and man.The Journal of Physiology, 1984
- Filter bleeding time: A new in vitro test of hemostasis I. Evaluation in normal and thrombocytopetic subjectsThrombosis Research, 1983