Invasion of the esophagus by Candida albicans probably occurs more frequently than the reported cases suggest. The disease usually occurs following immunosuppression but may occur after antibiotic therapy. It is heralded by the sudden onset of severe pain and dysphagia, and recovery or death from dissemination may occur. Roentgenographically, impaired motility is much more prominent than disordered motility or spasm. Narrowing, a cobblestone epithelium, and later, erosions and ulcerations are seen. Antifungal agents are adequate therapy.