Monensin inhibits synthesis of proteoglycan, but not of hyaluronate, in chondrocytes
- 15 January 1982
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 202 (1) , 249-254
- https://doi.org/10.1042/bj2020249
Abstract
Monensin (10 nM-1 .mu.M) inhibited the incorporation of [35S]sulfate and [3H]glucosamine into proteoglycans by rat chondrosarcoma cells, but the incorporation of [3H]glucosamine into hyaluronate was unaffected. Hyaluronate synthesis apparently occurs in a cell compartment separate from chondroitin sulfate synthesis.This publication has 12 references indexed in Scilit:
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