Caudate Lesions and Spontaneous Locomotion in the Monkey

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Abstract
Small lesions of the caudate nucleus have produced locomotor activity increases in monkeys, the extent of increase correlating with the volume of tissue damage. The effect is obtained for unilateral or bilateral lesions, and no "forced circling" is seen following a unilateral lesion. Large lesions result in "forced placing" immediately after operation, then giving to a period of activity increase in which the monkeys exhibit a great deal of climbing behavior. Floor pacing is the final observed behavior with these lesions.