Validity of the General Practice Research Database
Top Cited Papers
- 1 May 2003
- journal article
- research article
- Published by Wiley in Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
- Vol. 23 (5) , 686-689
- https://doi.org/10.1592/phco.23.5.686.32205
Abstract
The United Kingdom General Practice Research Database (GPRD) is an office‐based, computer‐generated, medical resource designed from its inception to be used for epidemiologic research. A distinct version of the GPRD is maintained by the Boston Collaborative Drug Surveillance Program and has been the source of more than 130 scientific articles primarily addressing drug safety issues. We reviewed evidence related to the validity of the GPRD. Specifically, with our extensive experience with this automated database, we evaluated the quality and completeness of the data that it contains.Keywords
This publication has 26 references indexed in Scilit:
- Live attenuated polio vaccine and the risk of intussusceptionBritish Journal of Clinical Pharmacology, 2001
- Are Schizophrenia or Antipsychotic Drugs a Risk Factor for Cataracts?Epidemiology, 2000
- Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal associationThe Lancet, 1999
- Tamoxifen and risk of idiopathic venous thromboembolismBritish Journal of Clinical Pharmacology, 1998
- Risk of venous thromboembolism in users of hormone replacement therapyThe Lancet, 1996
- Effect of different progestagens in low oestrogen oral contraceptives on venous thromboembolic diseaseThe Lancet, 1995
- Risk of idiopathic cardiovascular death and rionfatal venous thromboembolism in women using oral contraceptives with differing progestagen componentsThe Lancet, 1995
- Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugsThe Lancet, 1994
- Further validation of information recorded on a general practitioner based computerized data resource in the united kingdomPharmacoepidemiology and Drug Safety, 1992
- Validation of information recorded on general practitioner based computerised data resource in the United Kingdom.BMJ, 1991