Sucralfate and Gastric Bicarbonate
- 1 January 1985
- journal article
- Published by S. Karger AG in Pharmacology
- Vol. 31 (5) , 298-300
- https://doi.org/10.1159/000138136
Abstract
The effect of sucralfate treatment (3 g daily for 6 weeks) on gastric HCO3- secretion was investigated in 15 duodenal ulcer patients. After treatment a highly significant (p less than 0.01) increase in gastric bicarbonate output was found. It is suggested that the mode of action of sucralfate includes stimulation of gastric alkaline secretion.Keywords
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