RH-IMMUNE GLOBULIN AFTER AMNIOCENTESIS FOR GENETIC DIAGNOSIS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 48  (5) , 557-559
Abstract
Amniocentesis during the 2nd trimester of pregnancy for genetic diagnosis creates the potential for Rh sensitization secondary to fetomaternal bleeding. Administration of Rh-immune globulin after such amniocentesis is advised whenever the pregnancy may be Rh-incompatible. Of 56 patients who received Rh-immune globulin there was only 1 case of Rh sensitization, which occurred in a patient who underwent a 2nd amniocentesis 2 wk after the 1st attempt without receiving a 2nd dose of Rh-immune globulin. No developmental problems ascribed to Rh-immune globulin were detected.

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