EFFECT OF PARATHYROID EXTRACT ON BONE MATRIX HEXOSAMINE1
- 1 March 1961
- journal article
- other
- Published by The Endocrine Society in Endocrinology
- Vol. 68 (3) , 484-491
- https://doi.org/10.1210/endo-68-3-484
Abstract
The injection of parathyroid extract into normal and parathyroidectomized rats resulted in a decrease in bone matrix hexosamine. The effect was noted more promptly in the parathyroidectomized animals, as was the increase in serum calcium. Formaldehyde inactivated extract did not produce a similar decrease in the level of matrix hexosamine. These data suggest that the dissolution of organic bone matrix and calcium mobilization are closely correlated effects of parathyroid hormone.Keywords
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