Y Chromosome and Mitochondrial DNA Characterization of Pasiegos, a Human Isolate from Cantabria (Spain)
- 15 July 2003
- journal article
- research article
- Published by Wiley in Annals of Human Genetics
- Vol. 67 (4) , 329-339
- https://doi.org/10.1046/j.1469-1809.2003.00045.x
Abstract
Mitochondrial DNA sequences and Y chromosome haplotypes were characterized in Pasiegos, a human isolate from Cantabria, and compared with those of other Cantabrian and neighbouring Northern Spain populations. Cantabria appears to be a genetically heterogeneous community. Whereas Lebaniegos do not differ from their eastern Basque and western Asturian and Galician neighbours, Pasiegos and other non‐Lebaniego Cantabrians show significant differences with all of them. Pasiegos are peculiar for their high frequencies of Y chromosomal markers (E‐M81) with North African assignation, and Y chromosomal (R‐SRY2627) and mtDNA (V, I, U5) markers related to northern European populations. This dual geographic contribution is more in agreement with the complex demographic history of this isolate, as opposed to recent drift effects. The high incidence in Cantabrians with pre‐V and V mtDNA haplotypes, considered as a signal of Postglacial recolonization in Europe from south‐western refugees, points to such refugees as a better candidate population than Basques for this expansion. However, this does not discount a conjoint recolonization.Keywords
This publication has 25 references indexed in Scilit:
- A Signal, from Human mtDNA, of Postglacial Recolonization in EuropeAmerican Journal of Human Genetics, 2001
- Mitochondrial DNA characterisation of European isolates: The Maragatos from SpainEuropean Journal of Human Genetics, 2001
- Tracing European Founder Lineages in the Near Eastern mtDNA PoolAmerican Journal of Human Genetics, 2000
- An mtDNA Analysis in Ancient Basque Populations: Implications for Haplogroup V as a Marker for a Major Paleolithic Expansion from Southwestern EuropeAmerican Journal of Human Genetics, 1999
- Mitochondrial DNA analysis of Northwest African populations reveals genetic exchanges with European, Near‐Eastern, and sub‐Saharan populationsAnnals of Human Genetics, 1998
- Genetic diversity in Northern Spain (Basque Country and Cantabria): GM and KM variation related to demographic historiesEuropean Journal of Human Genetics, 1998
- mtDNA analysis of the Galician population: a genetic edge of European variationEuropean Journal of Human Genetics, 1998
- Phylogeography of mitochondrial DNA in western EuropeAnnals of Human Genetics, 1998
- Genetic diversity in the Iberian Peninsula determined from mitochondrial sequence analysisAnnals of Human Genetics, 1996
- Sequence and organization of the human mitochondrial genomeNature, 1981