The Leu33/Pro Polymorphism (PIA1/PIA2 ) of the Glycoprotein IIIa (GPIIIa) Receptor Is Not Related to Myocardial Infarction in the ECTIM Study
- 1 June 1997
- journal article
- platelets
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 77 (06) , 1179-1181
- https://doi.org/10.1055/s-0038-1656134
Abstract
The GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlAl/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls.Keywords
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