Smoking Habits and Age in Relation to Pulmonary Changes
- 14 November 1963
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 269 (20) , 1045-1054
- https://doi.org/10.1056/nejm196311142692001
Abstract
IT has been reported that cigarette smoking is highly associated with coughing and shortness of breath1 and with the clinical finding of chronic bronchitis.2 Furthermore, it has been shown experimentally that exposure to cigarette smoke produces marked changes in the vascular system of the lungs of rats.3 This led us to suspect that the lung parenchyma of human beings might be directly affected by chronic irritation from tobacco smoke or indirectly affected as a result of changes in the bronchial tubes. Therefore, we undertook a histologic study of tissue from peripheral portions of the lungs. All the lungs in this . . .Keywords
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