HUMAN PAPILLOMAVIRUS DEOXYRIBONUCLEIC-ACID IN ADENOCARCINOMA AND ADENOSQUAMOUS CARCINOMA OF THE UTERINE CERVIX
- 1 August 1986
- journal article
- research article
- Vol. 68 (2) , 241-244
Abstract
This report describes the detection of human papillomavirus type 16 or 18 deoxyribonucleic acid (DNA) in nine of 15 invasive tumors of the cervix, including three squamous carcinomas, four adenosquamous carcinomas, one glassy cell carcinoma, and one adenocarcinoma. The viral DNA was identified by Southern blotting and DNA hybridization. Human papillomaviruses may play an etiologic role in the development of at least some adenocarcinomas and adenosquamous carcinomas as well as most squamous tumors of the cervix.This publication has 6 references indexed in Scilit:
- A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.The EMBO Journal, 1984
- Adenocarcinoma In Situ of the CervixInternational Journal of Gynecological Pathology, 1984
- Variable-sized free episomes of Shope papilloma virus DNA are present in all non-virus-producing neoplasms and integrated episomes are detected in some.Proceedings of the National Academy of Sciences, 1982
- COEXISTENCE OF CERVICAL INTRA-EPITHELIAL NEOPLASIA WITH PRIMARY ADENOCARCINOMA OF THE ENDOCERVIX1980
- Noninvasive precursor lesions of adenocarcinoma and mixed adenosquamous carcinoma of the cervix uteriCancer, 1979
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977