Studies of nonsedative antihistamines. II. Assessment of its antihistaminic potency.

  • 1 September 1992
    • journal article
    • research article
    • Vol. 20  (5) , 207-10
Abstract
An analysis is made of the effectiveness of terfenadine at dosages of 60 and 120 mg, of cetirizine at a dose of 10 mg, and of loratadine and ebastine at a dose of 10 mg in inhibiting the papule induced by 20 mcg of intradermal histamine. Although all produced significant inhibition, cetirizine and terfenadine 120 mg showed a significantly greater inhibition coefficient than loratadine.

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