Common childhood and adolescent infections and multiple sclerosis
- 1 August 1997
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 49 (2_suppl_2) , S42-S54
- https://doi.org/10.1212/wnl.49.2_suppl_2.s42
Abstract
While the occurrence of true clusters is still debated, the existence of a temporal trend, both decreasing and increasing, in several countries strongly supports the view that the heterogeneity of the temporal distribution could be linked to the influence of exogenous factors and, moreover, provide clues to the characteristics of the unknown and probably multiple etiologic factors that influence the appearance of MS in genetically prone subjects. These exogenous agents may modify their concentration and aggressiveness over time. Such characteristics are indicative of infectious agents.2,3Keywords
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