A ribosomal protein gene family from Schizosaccharomyces pombe consisting of three active members

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Abstract
Recently, we have reported the isolation and characterization of a ribosomal protein gene from the fission yeast Schizosaccharomyces pombe. This gene was called K37. Here we describe the isolation of two genes which are related to the K37 gene. Sequence analysis of these genes revealed open reading frames encoding proteins which are almost identical to the ribosomal protein K37. Furthermore, all three genes are functional as determined by Northern analysis using transformed and wild type cells. The results indicate that S. pombe contains a ribosomal protein gene family, designated the K-family, consisting of three active members. The promoter regions of the three members are compared and several common motifes are identified which might serve as transcriptional activators in these genes.