New Camptothecin and Ellagic Acid Analogues from the Root Bark ofCamptotheca acuminata
- 1 December 2004
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 70 (12) , 1216-1221
- https://doi.org/10.1055/s-2004-835854
Abstract
As part of a study on chemical constituents of Camptotheca species, one new natural camptothecin analogue (2), two new alkaloids (3, 4), one new ellagic acid analogue (5), and 19 known compounds (1, 6 - 23) have been isolated from the root bark, stem bark, fruits, and leaves of Camptotheca acuminata Decaisne. The structures of 2 - 5 were determined from spectral data to be 10-methoxy-20-O-acetylcamptothecin (2), 20-O-β-glucopyranosyl 18-hydroxycamptothecin (3), 20-formylbenz[ 6 ] [ 7 ]indolizino [1,2-b]quino-line-11(13H)-one (4), and 3,4-methylenedioxy-3′-O-methyl-5′-hydroxyellagic acid (5).Keywords
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