Nachtrag zu der Arbei „Vergebliche Versuche zur Abtrennung des antirachitischen vom toxischen Faktor in Bestrahlungsprodukten des Ergosterins“.
- 1 January 1931
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 202 (4-6) , 246-248
- https://doi.org/10.1515/bchm2.1931.202.4-6.246
Abstract
By heating at 200[degree] or by hydrogenation the original irradiated ergosterol lost its antirachitic but retained its toxic property. The antirachitic and toxic substances in the original irradiation product combined readily with maleic anhydride. After hydrogenation or heating the combination of the toxic substance with maleic anhydride took place less readily. Hence the toxic substances in the original and treated irradiation products are different. A crystalline preparation of the vitamin showed toxic action in high doses, suggesting that the vitamin is responsible for both properties.This publication has 0 references indexed in Scilit: