Systemic Factors That Influence the Manifestations of Osteolathyrism in the Periodontium

Abstract
Systemic conditioning agents modified the severity of osteolathyritic changes induced in the periodontium of rats by administration of 10 mg of amino-acetonitrile (AAN)/day. The lathyritic manifestations in the periodontium were accentuated by partial hepatectomy, thyroparathyroid-ectomy and thyroparathyroidectomy plus thyroxin (1 [mu]g/day); and reduced by ACTH (10 I. U./day); and almost complete nullified by thyroxin (500 [mu]g/day).