Aldol Reactions of Acylsilanes and Difluoroenoxysilanes. Application to the Synthesis of 2-Fluoro-1,3-diketones
- 1 April 1999
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1999 (4) , 432-434
- https://doi.org/10.1055/s-1999-2632
Abstract
We describe the synthesis of new gem-difluoro-C-silylated aldols from acylsilanes and trifluoromethyltrimethylsilane via an aldol reaction. Their defluorosilylation gives aliphatic and alicyclic 2-fluoro-1,3-diketones. The overall reaction sequence can be considered as a new complementary method giving access to a wide variety of such fluorinated 1,3-diketones.Keywords
This publication has 0 references indexed in Scilit: