The Skin Changes in the Crow-Fukase (POEMS) Syndrome

Abstract
• A man with a six-year history of intermittent burning sensations in his legs, hypothyroidism, and peripheral neuropathy also had hypertrichosis, hyperpigmentation, Terry nails, and taut thickened skin of the extremities. Discovery of a plasma cell tumor led to recognition of the Crow-Fukase syndrome, and appropriate treatment with melphalan and prednisone. (Arch Dermatol 1987;123:85-87)

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