Human-Derived Immune Globulins for the Treatment of Botulism
- 1 July 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 1 (4) , 689-692
- https://doi.org/10.1093/clinids/1.4.689
Abstract
The need for a human-derived immune globulin .to replace the equine antitoxins currently used in the treatment of botulism is well recognized. A small group of individuals who had received multiple immunizations with pentavalent botulinal toxoid were plasmapheresed for the purpose of collecting a botulism-immune plasma of human origin to be fractionated for the production of immune globulin. Human-derived immune globulin will offer the advantage over equine antitoxins of not inducing reactions to foreign protein and of having a prolonged effective half-life.Keywords
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