Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding.
Open Access
- 4 January 1994
- journal article
- abstracts
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 269 (1) , 277-283
- https://doi.org/10.1016/s0021-9258(17)42346-5
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Novel Fold and Putative Receptor Binding Site of Granulocyte-Macrophage Colony-Stimulating FactorScience, 1991
- Dimerization of the Extracellular Domain of the Human Growth Hormone Receptor by a Single Hormone MoleculeScience, 1991
- A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSFCell, 1991
- Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptorsCell, 1991
- Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.Proceedings of the National Academy of Sciences, 1990
- A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalizationCell, 1989
- A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor β-chainBiochemical and Biophysical Research Communications, 1989
- Interleukin-2 Receptor β Chain Gene: Generation of Three Receptor Forms by Cloned Human α and β Chain cDNA'sScience, 1989
- An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2Nature, 1987
- LIGAND: A versatile computerized approach for characterization of ligand-binding systemsAnalytical Biochemistry, 1980