A High Pressure Liquid Chromatographic Procedure for Monitoring

Abstract
A reverse phase high pressure liquid chromatographic method was developed for the analysis of 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) levels present in body fluids. A value obtained for the plasma half-life for a single patient indicates that this may be larger than expected.

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