Examination of the Cerebro-spinal Fluid as an Aid to Diagnosis in Certain Cases of Insanity, with Special Reference to the Protein Reaction described by Ross and Jones

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Abstract
The value of Wassermann's reaction in the diagnosis of syphilitic and the so-called para-syphilitic diseases is now generally conceded, but, apart from the technical difficulties in carrying out the test, which places it beyond the means of all except those working in well-equipped laboratories specially licensed, the fact that it merely enables one to diagnose a previous syphilitic infection in nearly all its stages, detracts somewhat from its value as a means for the special diagnosis of general paralysis or tabes. Wassermann's reaction tells us what nearly every patient is able, if willing, to tell us; whereas the protein reactions, especially that described by Ross and Jones, appear, so far at any rate as my observations go, to be much more specific in the information they yield. The Ross-Jones test in my hands only gave a positive result in general paralysis and cerebral syphilis.

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