Basic Biological Sciences Reserpinization: Effects on Parotid Gland Function
- 1 February 1984
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 63 (2) , 82-86
- https://doi.org/10.1177/00220345840630021401
Abstract
Chronic reserpinization of mice and rabbits affected parotid gland function; cholinergic and β-adrenergic-stimulated amylase release were significantly reduced, and cyclic-AMP and cyclic-GMP levels were significantly elevated above control-stimulated levels. Amylase released by dibutyryl-c-AMP was also reduced, suggesting a defect in stimulus-secretion coupling subsequent to c-AMP formation.Keywords
This publication has 25 references indexed in Scilit:
- Does cyclic GMP mediate amylase release from mouse parotid acini?Life Sciences, 1982
- Effect of sodium ions on cyclic AMP and cyclic GMP levels in mouse parotid aciniLife Sciences, 1982
- Phosphorylation of rabbit parotid microsomal protein occurs only with β-adrenergic stimulationBiochemical and Biophysical Research Communications, 1981
- Impaired amylase release from the parotid gland of rats treated with reserpineCellular and Molecular Life Sciences, 1979
- Chronically Reserpinized Rat as a Model for Cystic Fibrosis: Na+ Transport Inhibitory Effect in Submaxillary SalivaPediatric Research, 1979
- Effect of Chronic Reserpine Administration on K+ and Amylase Release from the Rat Parotid GlandPediatric Research, 1979
- Electrolyte and energy changes following parasympathomimetic and sympathomimetic stimulation in submandibular salivary glands of rats treated with reserpineArchives of Oral Biology, 1979
- Sodium nitroprusside and other smooth muscle-relaxants increase cyclic GMP levels in rat ductus deferensNature, 1977
- Neuronal localization of the enhanced adenylate cyclase responsiveness to catecholamines in the rat cerebral cortex following reserpine injectionsNeuropharmacology, 1976
- The role of calcium and cyclic nucleotides in α-amylase release from slices of rat parotid: Studies with the divalent cation ionophore A-23187Metabolism, 1975