1-Methyl-4-phenylpyridinium (MPP+) but not 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) selectively destroys dopaminergic neurons in cultures of dissociated rat mesencephalic neurons
- 1 December 1986
- journal article
- research article
- Published by Elsevier in Neuroscience Letters
- Vol. 72 (2) , 215-220
- https://doi.org/10.1016/0304-3940(86)90083-2
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Deprenyl Protects Dopamine Neurons from the Neurotoxic Effect of 1‐Methyl‐4‐Phenylpyridinium IonJournal of Neurochemistry, 1985
- Catecholamine-uptake inhibitors prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brainNeuropharmacology, 1985
- 1-methyl-4-phenylpyridine (MPP+) is toxic to mesencephalic dopamine neurons in cultureNeuroscience Letters, 1985
- IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effectsLife Sciences, 1985
- Neurochemical and Histochemical Characterization of Neurotoxic Effects of 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine on Brain Catecholamine Neurones in the MouseJournal of Neurochemistry, 1985
- V. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Life Sciences, 1985
- Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitorsNature, 1984
- Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonismNature, 1984
- 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Destroys Dopamine Neurons in Explants of Rat Embryo MesencephalonScience, 1984
- Serum Factor Supporting Long-Rerm Survival of Rat Central Neurons in CultureScience, 1983