Synthese von Pyrazolo[3,4‐b]chinolinen aus 4‐Aroyl‐5‐chlor‐pyrazolen
- 1 January 1990
- journal article
- research article
- Published by Wiley in Journal für Praktische Chemie
- Vol. 332 (5) , 693-698
- https://doi.org/10.1002/prac.19903320518
Abstract
Synthesis of Pyrazolo[3,4‐b]quinolines from 4‐Aroyl‐5‐chloropyrazolesThe reaction of 4‐aroyl‐5‐chloro‐3‐methyl‐1‐phenyl‐pyrazoles 1 with an excess of 3‐ or 4‐substituted and 3,4‐disubstituted anilines 2 gives pyrazolo [3,4‐b]quinolines 4a‐k. Information about the reaction mechanism was obtained by the isolation of the intermediate product 3e. In some cases it was possible to isolate subsequent products 41‐p. The reaction of 1a with 5‐amino‐3‐methyl‐1‐phenyl‐pyrazole (5) gives a bispyrazolopyridine derivative 6.Keywords
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