SPECIFIC HARMFULNESS OF RESPIRABLE DUSTS FROM WEST GERMAN COAL MINES I: RESULTS OF CELL TESTS
- 1 June 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Annals of Occupational Hygiene
- Vol. 26 (4) , 473-479
- https://doi.org/10.1093/annhyg/26.4.473
Abstract
For research on the specific harmfulness of fine dusts from 43 coal faces of the Ruhr and Saar District, 120 fine dust samples had been taken with BAT-I and BAT-II instruments. The biological effect of these samples in cell and animal experiments has been examined in relation to their mineral, chemical and physical properties. It needs to be established whether these results are in accordance with those of epidemiological investigations. Cell experiments by the TTC-test indicated a strongly increasing cytotoxicity of dusts from lower strata with (low) mineral content in the range from 7 to 20%. This tendency of cytotoxicity to increase with rising mineral content strongly diminishes in dust samples from the upper strata (mineral content 30 to 70%). There is no linear increase of cytotoxicity with rising quartz content (from about 3%). Within a stratigraphic horizon the dust samples examined showed no significant relation between cytotoxicity and quartz content.Keywords
This publication has 0 references indexed in Scilit: