Abstract
Peptic ulcers and other suggestions of depression appear in histories of accident victims, indicating that disability exists before the mishap. After the accident has occurred, this disability is linked with an apparent physical defect, and it becomes acceptable to both patient and society. Breaking this linkage is an important factor in successful therapy. Of equal interest is the fact that prior depression has measurable physical components. Increases occur in adrenal and gastric secretions. Ketosteroid, metadrenalin, normetadrenal, thyroid, and estrogen titers change, some in blood, others in urine. Such physical variables of preaccident depression could be measured for prediction and possibly for preventive therapy.

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