Changes in lipoprotein‐lipase activity and lipid stores in human skeletal muscle with prolonged heavy exercise

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Abstract
Lipoprotein-lipase (LPL) activity and intracellularly stored triglycerides were determined in muscle biopsies taken from 7 volunteers before and after an 85 km skiing race. The triglyceride stores were larger in slow twitch than in fast twitch fibers (proportions 5:1 before the race). The LPL activity increased and the triglyceride stores in slow twitch fibers decreased during the race. The best trained subjects had the largest TG stores before the race and their TG stores also decreased most during the race. These subjects also had very small increases of LPL activity. The least trained subject showed a 6-fold increase in LPL activity. The high post-race LPL activity in less trained subjects indicates a higher capacity for uptake of fatty acids from serum TG as compared to the more trained subjects.