Abstract
The article by Lassau et al. [1] on the use of contrast-enhanced Doppler ultrasound (Doppler US) for early and rapid assessment of tumour response after isolated limb perfusion (ILP) for locally advanced soft tissue sarcomas (STSs) of the extremities is an excellent example of the new opportunities that arise with rapidly evolving technologies in imaging. In the quest for early predictors and surrogate markers for response this technology represents a relatively simple, practical and cheap procedure.