Malakoplakia of the colon and recurrent colonic strictures in a patient with primary hypogammaglobulinemia

Abstract
A 9 yr old boy with primary hypogammaglobulinemia and recurrent colonic strictures who developed malakoplakia of the colon is reported. The development of colonic strictures is not considered a gastrointestinal manifestation of hypogammaglobulinemia. Malacoplakia of the colon is a rare disease, with 26 cases being reported to date. Only 5 children under age 13 have been reported with colonic malakoplakia and none with hypogammaglobulinemia. Hypogammaglobulineamia should be added to the growing list of conditions predisposing to the development of malakoplakia.

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