CRP and the disposal of dying cells: Consequences for systemic lupus erythematosus and rheumatoid arthritis
- 1 January 2007
- journal article
- review article
- Published by Taylor & Francis in Autoimmunity
- Vol. 40 (4) , 295-298
- https://doi.org/10.1080/08916930701358925
Abstract
C reactive protein (CRP) levels directly correlate with the disease activity of many inflammatory diseases, e.g. sepsis, infection, and various autoimmunopathies such as rheumatoid arthritis (RA) . In contrast, insufficient CRP levels are implicated in the development of systemic lupus erythematosus (SLE) . This article reports on the level-depended effects of CRP in various diseases. In detail we show that increased and decreased levels of CRP, as demonstrated in patients with RA and SLE, respectively can contribute to disease progression.Keywords
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