Liddle Syndrome: Clinical and Cellular Abnormalities
- 15 July 1994
- journal article
- research article
- Published by Taylor & Francis in Hospital Practice
- Vol. 29 (7) , 95-105
- https://doi.org/10.1080/21548331.1994.11443050
Abstract
Clinical findings resemble those of primary hyperaldosteronism, except that aldosterone secretion is negligible. The fault appears to lie with continuously avid sodium channels in the distal nephron, resulting in excessive salt absorption, potassium wasting, and severe hypertension. Insights gained in this disorder may help clarify more common forms of low-renin hypertension.Keywords
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