Nitric oxide inhibits the cytochrome oxidase but not the alternative oxidase of plant mitochondria
- 2 December 1996
- journal article
- Published by Wiley in FEBS Letters
- Vol. 398 (2-3) , 155-158
- https://doi.org/10.1016/s0014-5793(96)01230-6
Abstract
Oxygen consumption via the cytochrome pathway in isolated soybean (Glycine max [L.] Merr.) cotyledon mitochondria was inhibited by nitric oxide (NO) while respiration via the cyanide‐insensitive alternative oxidase was not significantly affected. Inhibition of cytochrome pathway activity was rapidly reversible upon depletion of the added NO. NO production was also detected in solutions of NaNO2 plus ascorbate and the extent of cytochrome pathway inhibition was dependent on the NO2 − concentration. Little inhibition of alternative pathway respiration was observed under similar conditions. The alternative oxidase may play a role in nitric oxide tolerance in higher plants and in organisms such as trypanosomes which contain a plant‐like alternative oxidase.Keywords
This publication has 22 references indexed in Scilit:
- Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxidePublished by Wiley ,2001
- Mitochondrial Nitric Oxide Synthase: A Ubiquitous Regulator of Oxidative Phosphorylation?Biochemical and Biophysical Research Communications, 1996
- Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivoParasite Immunology, 1995
- Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidaseFEBS Letters, 1994
- Comparison between NOx Evolution Mechanisms of Wild-Type and nr1 Mutant Soybean LeavesPlant Physiology, 1990
- The Conversion of Nitrite to Nitrogen Oxide(s) by the Constitutive NAD(P)H-Nitrate Reductase Enzyme from SoybeanPlant Physiology, 1988
- Biochemical Characterization of Chlorophyll-Free Mitochondria From Pea LeavesFunctional Plant Biology, 1985
- The Cyanide-Resistant, Alternative Path in Higher Plant RespirationAnnual Review of Plant Physiology, 1982
- Nitric oxide (NO) and nitrogen dioxide (NO2) emissions from herbicide-treated soybean plantsAtmospheric Environment (1967), 1979
- Respiratory Mechanisms in the Aroid SpadixJournal of Experimental Botany, 1957