Ciprofloxacin resistance in methicillin-and gentamicin-resistantStaphylococcus aureus

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Abstract
A total of 112Staphylococcus aureus strains resistant to methicillin and gentamicin were collected from 31 centres in 22 countries worldwide. Many strains were multi-resistant. In tests to determine the susceptibility of the organisms to ciprofloxacin 16 strains (14.3%), originating from France, the FRG, Israel and Italy, were shown to be resistant to this agent. To limit ciprofloxacin resistance, a reappraisal is necessary of fluoroquinolone usage against methicillin-and gentamicin-resistantStaphylococcus aureus.