Tissue-specific expression of a Drosophila calcium-activated potassium channel
Open Access
- 1 September 1995
- journal article
- Published by Society for Neuroscience in Journal of Neuroscience
- Vol. 15 (9) , 6250-6259
- https://doi.org/10.1523/jneurosci.15-09-06250.1995
Abstract
The Drosophila slowpoke (slo) gene encodes a subunit of a CAK channel homologous to the vertebrate BK channel. We have examined slo expression throughout development. It is expressed in muscle cells, neurons of the CNS and PNS, mushroom bodies, a limited number of cells in embryonic and larval midgut and in epithelial-derived tracheal cells. The promoter has been cloned and shown to direct expression in the same pattern as the endogenous gene in both neural and epithelial- derived cells. During pupariation and embryogenesis, slo is expressed in muscles many hours prior to the appearance of functional channels.Keywords
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