Combination of the ADH with a Two-dimensional Synthesis
- 1 October 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (10) , 1029-1030
- https://doi.org/10.1055/s-1995-5158
Abstract
Asymmetric dihydroxylation of the symmetrical diester 1 provided after lactonization the C2-symmetric bis-lactone 3. The chiral information was then propagated by a double alkylation reaction. After conversion of the alkylated bis-lactone 4a to the diol 8, a cleavage reaction provided the chiral building block 9.Keywords
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