Increased Sensitivity to Pesticides in Sheepshead Minnows

Abstract
The possibility of inducing genetic resistance to pesticides in fish was investigated by exposing mature sheepshead minnows (Cyprinodon variegatus) to concentrations of DDT exceeding the median tolerance limit, then transferring survivors to field pools to reproduce. Groups of fish suffering mortality greater than 90% produced young significantly more sensitive to both DDT and endrin than controls, whereas the offspring of groups in which mortality ranged from 55 to 90% were more sensitive than control fish to endrin, but not to DDT.

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