Tremor Production in Cats Given Chlorpromazine

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Abstract
In a series of 28 cats injected with varying doses of chlorpromazine, 13 (46%) developed tremors. The basic tremor was present at rest and disappeared on movement. The rhythm was most often 6-8/second, but a few animals displayed a faster or slower rate. The tremor was reversible and reproducible. Implications of these observations relative to human parkinsonism are discussed.