Carcinoembryonic antigen: Function in metastasis by human colorectal carcinoma
- 1 December 1989
- journal article
- review article
- Published by Springer Nature in Cancer and Metastasis Reviews
- Vol. 8 (3) , 263-280
- https://doi.org/10.1007/bf00047341
Abstract
Carcinoembryonic antigen (CEA) is a glycoprotein that has been useful as a tumor marker to predict recurrence in gastrointestinal malignancies, but whose biological function has not been elucidated. With the recent evidence that CEA is a member of the immunoglobulin supergene family, CEA may be involved in intercellular recognition and binding. This review examines the role that CEA plays in the development of mestastases by colorectal carcinoma.Keywords
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